The Longevity Archive
All compounds

Hormone

15 evidence-rated hormone compounds.

Gonadorelin

Gonadorelin (synthetic GnRH)

Moderate

Synthetic gonadotropin-releasing hormone, historically approved for diagnosis and fertility and now used to preserve testicular function during testosterone therapy.

HormoneRev. Sep 2026

Kisspeptin-10

Kisspeptin-10

Moderate

A reproductive neuropeptide that triggers the body's own GnRH release, studied for fertility, hypogonadism, and sexual response.

HormoneRev. Sep 2026

Oxytocin

Oxytocin

Moderate

A natural hormone that is FDA-approved for labor and is also studied, with mixed results, for social, bonding, and psychiatric effects.

HormoneRev. Sep 2026

HCG

Human Chorionic Gonadotropin

Strong

An FDA-approved gonadotropin used in fertility and to maintain testicular function and testosterone production in men.

HormoneRev. Sep 2026

Vasopressin

Vasopressin (antidiuretic hormone, AVP)

Strong

The natural water-retention hormone, FDA-approved as a drug to raise blood pressure in critically ill patients.

HormoneRev. Sep 2026

Desmopressin

Desmopressin (DDAVP, vasopressin analogue)

Strong

An FDA-approved vasopressin analogue for diabetes insipidus, bedwetting, and certain bleeding disorders.

HormoneRev. Sep 2026

Octreotide

Octreotide (somatostatin analogue)

Strong

An FDA-approved long-acting somatostatin analogue used for acromegaly and hormone-secreting tumors.

HormoneRev. Sep 2026

Teriparatide

Teriparatide (parathyroid hormone 1-34)

Strong

An FDA-approved bone-building peptide, a fragment of parathyroid hormone used for severe osteoporosis.

HormoneRev. Sep 2026

Abaloparatide

Abaloparatide (PTHrP analogue)

Strong

An FDA-approved bone-building peptide analogue of parathyroid hormone-related protein for postmenopausal osteoporosis.

HormoneRev. Sep 2026

Calcitonin

Calcitonin (salmon calcitonin)

Moderate

A hormone that lowers blood calcium, FDA-approved (as salmon calcitonin) for osteoporosis, Paget's disease, and high calcium.

HormoneRev. Sep 2026

Leuprolide

Leuprolide (GnRH agonist)

Strong

An FDA-approved GnRH agonist that suppresses sex hormones, used for prostate cancer, endometriosis, and precocious puberty.

HormoneRev. Sep 2026

Goserelin

Goserelin (GnRH agonist)

Strong

An FDA-approved GnRH agonist implant that suppresses sex hormones for prostate and breast cancer and endometriosis.

HormoneRev. Sep 2026

Cetrorelix

Cetrorelix (GnRH antagonist)

Strong

An FDA-approved GnRH antagonist used in fertility treatment to prevent premature ovulation.

HormoneRev. Sep 2026

Navepegritide

Navepegritide (TransCon CNP, Yuviwel)

Strong

A once-weekly prodrug of C-type natriuretic peptide, FDA-approved in February 2026 for achondroplasia in children aged two and older.

HormoneRev. Sep 2026

Enclomiphene

Enclomiphene citrate

Moderate

The trans isomer of clomiphene, prescribed off-label through compounding to raise testosterone while preserving sperm production; never FDA-approved on its own after repeated complete response letters.

HormoneRev. Sep 2026