Thymogen
Thymogen (Glu-Trp dipeptide)
A synthetic dipeptide immune modulator derived from thymus peptide research, used in Russia to support immune function.
Overview
Thymogen is a synthetic dipeptide of glutamic acid and tryptophan, identified as an active fragment within thymus-derived immune peptides. It is used in Russia as an immune modulator for infections and immune suppression. Independent evidence is limited, and it is not FDA-approved. It is closely related conceptually to the thymic peptide family.
Mechanism of action
Proposed to modulate T-cell function and immune regulation as a minimal active fragment of thymic peptides.
Key studies & citations
- Human1996
Thymogen in the treatment of type-1 diabetes mellitus
Russian clinical report: thymogen reversed signs of secondary immunodeficiency via T-lymphocyte differentiation; uncontrolled design.
Terapevticheskii Arkhiv - Review2024
The first reciprocal activities of chiral peptide pharmaceuticals: thymogen and thymodepressin, as examples
Review of the Glu-Trp dipeptide thymogen and its D-isomer counterpart thymodepressin as opposite-acting immunomodulators.
International Journal of Molecular Sciences
Frequently asked questions
How does Thymogen relate to Thymalin?
Thymogen is a defined dipeptide identified as an active fragment within thymic peptide preparations like Thymalin. Both come from the thymic immune-peptide research tradition.