Legal status · Canada
Is BRP legal in Canada?
No. BRP is not an approved medicine in Canada; its classification is "Not authorized for sale". Nothing containing it is authorized for any use in people. Vials labeled "for research use only" are not exempt: that label does not make human use lawful. Human evidence: Preliminary.
BRP in Canada at a glance
| Classification | Not authorized for sale |
|---|---|
| Health Canada approval status | Not approved by Health Canada |
| Evidence level | Preliminary (research strength: Preliminary) |
| Reviewed | Sep 2026 |
Classification and note come from the BRP profile, checked against Health Canada, Health Products and Food Branch (Health Canada) listings at the reviewed date.
What this means
- 01
No product containing BRP is approved by Health Canada for any use in Canada, so nothing on the market is authorized for people.
- 02
"Research use only" is a vendor label, not a legal category that permits human use. It does not exempt a product from medicines law.
- 03
Importing, supplying or promoting it for human use can fall under medicines legislation in Canada. This page is general information, not legal advice.
What BRP is
A 12 amino acid peptide discovered by AI-guided prohormone screening at Stanford that cut food intake by up to half in mice and minipigs through a non-GLP-1 pathway; no human trial exists.
BRP was reported in Nature in March 2025 after an algorithm predicted cleavage products of prohormones. A single injection reduced food intake by as much as 50% over an hour in lean mice and minipigs without the aversion behaviors seen with GLP-1 drugs, acting on hypothalamic POMC neurons.
Mechanism: Activates hypothalamic POMC neurons via cAMP-PKA-CREB signaling, a pathway distinct from the GLP-1 receptor.
Regulatory history: Preclinical; no IND
How Health Canada treats this kind of product
Authorises drugs for sale through a Notice of Compliance and Drug Identification Number. A compound that is not authorised for sale cannot lawfully be sold for human use, and personal importation of prescription drugs is limited.
The classification above is the The Longevity Archive reading of Health Canada, Health Products and Food Branch listings for BRP at the reviewed date, not a legal opinion. Rules change, and importing, prescribing and possessing a compound can each be treated differently. Check the regulator directly before acting on anything here.
BRP in other countries
United States
Not approvedNot approved; sold 'for research use only'
Is BRP legal in the United States?United Kingdom
Not approvedUnlicensed medicine; supply for human use is unlawful
Is BRP legal in the United Kingdom?Australia
Not approvedNot approved; Schedule 4 or import-restricted
Is BRP legal in Australia?Frequently asked questions
Is BRP legal in Canada?
No. BRP is not an approved medicine in Canada; its classification is "Not authorized for sale". Nothing containing it is authorized for any use in people. Vials labeled "for research use only" are not exempt: that label does not make human use lawful. Human evidence: Preliminary.
Can I buy BRP in Canada?
No approved product exists to buy. In Canada BRP is classified as "Not authorized for sale", so there is no licensed pharmacy product. Vendors selling it "for research use only" are not selling it for human use, and that label does not change its legal status. This site does not list or recommend vendors.
Is BRP Health Canada approved?
No. In Canada BRP is classified as "Not authorized for sale", which is not a Health Canada marketing approval. For comparison, the US FDA status is: Preclinical; no IND. Evidence level: Preliminary.
Related compounds in Canada
Full research profile
Mechanism, cited studies, FDA status and the full legal summary for BRP live on its compound profile.
BRP profileThis page is general information about the regulatory status of BRP in Canada, current as of Sep 2026. It is not legal advice, and classifications change; check Health Canada, Health Products and Food Branch directly or consult a lawyer for a specific situation. Educational use only. This database summarizes published research. It is not medical advice and contains no dosing protocols or recommendations for personal use. The Longevity Archive has no vendor relationships and does not recommend where to buy anything.