The Longevity Archive
All compounds

Immune

9 evidence-rated immune compounds.

Thymosin Alpha-1

Thymosin Alpha-1 (Thymalfasin)

Moderate

An immune-modulating thymic peptide approved in many countries for hepatitis and used as an immune adjuvant.

ImmuneRev. Sep 2026

Thymalin

Thymalin (thymic peptide bioregulator)

Preliminary

A thymus-derived peptide preparation studied in Russian research for restoring age-related immune decline.

ImmuneRev. Sep 2026

LL-37

LL-37 (human cathelicidin antimicrobial peptide)

Preliminary

The main human cathelicidin antimicrobial peptide, central to innate immunity and wound healing, with a complex double-edged role in disease.

ImmuneRev. Sep 2026

Thymogen

Thymogen (Glu-Trp dipeptide)

Preliminary

A synthetic dipeptide immune modulator derived from thymus peptide research, used in Russia to support immune function.

ImmuneRev. Sep 2026

Thymopentin

Thymopentin (TP-5, thymopoietin fragment)

Moderate

A pentapeptide fragment of thymopoietin studied and used in some countries as an immune modulator.

ImmuneRev. Sep 2026

Thymulin

Thymulin (zinc-dependent thymic hormone)

Preliminary

A zinc-dependent thymic hormone studied for immune regulation, inflammation, and pain, mostly in preclinical work.

ImmuneRev. Sep 2026

PNC-27

PNC-27, p53-derived membrane-active peptide

Preliminary

An in-vitro cancer-cell-lysing peptide sold online as a cancer cure in nebulized, injectable and other forms; the FDA warned the public after finding bacterial contamination in a product, and no human trial has ever been registered.

ImmuneRev. Sep 2026

Bronchogen

Bronchogen (Ala-Glu-Asp-Leu, AEDL)

Preliminary

A Khavinson tetrapeptide sold for lung and bronchial health; in-vitro work only, from one group, with no human trials or pharmacokinetics.

ImmuneRev. Sep 2026

Chonluten

Chonluten (Glu-Asp-Gly, EDG)

Preliminary

A Khavinson tripeptide sold for lung and mucosal health; patent-level and single-paper evidence.

ImmuneRev. Sep 2026